Public academic profile

Luke O'neill

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Luke O'neill

Environment Agency

Immune Response and InflammationInflammasome and immune disordersNF-κB Signaling PathwaysImmune cells in cancerinterferon and immune responses
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707Works
99,185Citations
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Research publications

Recent works publicly associated with this researcher.

Impact of antibiotic side effects and allergies on patient adherence and attitudes: a mixed methods study in England

2025 · BJGP Open · 1 citations

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Mitochondrial glutathione transporter SLC25A40 regulates macrophage cytokine production

2025 · Scientific Reports · 3 citations

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107 PKM2 is a promising novel target in atopic dermatitis

2025 · Journal of Investigative Dermatology · 0 citations

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Phospholipid metabolism in innate immunity and inflammation: from basic to clinic

2025 · Immunity & Inflammation · 14 citations

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In vitro protocol demonstrating five functional steps of trained immunity in mice: Implications on biomarker discovery and translational research

2025 · Cell Reports · 5 citations

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Adenosine 2A receptor–dependent activation of AMPK represses T <sub>H</sub> 17 cell pathogenicity through epigenetic and metabolic reprogramming

2025 · Science Signaling · 0 citations

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Targeting complex IV to alter the tumor microenvironment and boost macrophage antitumor immunity

2025 · Life Metabolism · 2 citations

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Lessons from Glucocorticoids, Metformin, and Dimethyl Fumarate: Could Targeting Immunometabolism Lead to Better Anti-Inflammatory Therapies?

2025 · The Annual Review of Pharmacology and Toxicology · 8 citations

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Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models

2025 · Frontiers in Immunology · 3 citations

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4-octyl itaconate reduces human NLRP3 inflammasome constitutive activation with the cryopyrin-associated periodic syndrome p.R262W, p.D305N and p.T350M variants

2025 · Cellular and Molecular Life Sciences · 5 citations

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RETRACTED ARTICLE: MAVS is a sensor of fumarate during antiviral immunity

2025 · Nature Microbiology · 1 citations

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Gang of 3: How the Krebs cycle-linked metabolites itaconate, succinate, and fumarate regulate macrophages and inflammation

2025 · Cell Metabolism · 90 citations

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Preventing and managing urinary tract infections: Exploring interventions and strategies implemented by NHS commissioning organisations in English primary care, 2017–2022

2025 · Journal of Infection Prevention · 0 citations

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Recycling dead bacteria to fuel macrophage immunometabolism

2025 · Nature Immunology · 1 citations

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Trained immunity causes myeloid cell hypercoagulability

2025 · Science Advances · 9 citations

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Mitochondrial respiratory complex III sustains IL-10 production in activated macrophages and promotes tumor-mediated immune evasion

2025 · Science Advances · 29 citations

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Clinical stage drugs utilizing cellular metabolism pathways

2025 · Elsevier eBooks · 0 citations

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The metabolism revolution: you need energy to fight and to live

2025 · Elsevier eBooks · 0 citations

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Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine

2025 · Cell Reports · 42 citations

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